2. Lexus RX 350

The Lexus RX 350 should not fool you with its daring style —it’s still the plush-riding crossover it’s always been, but a technological leap forward from its segment-defining predecessor. It offers two configurations a 295-hp V-6, eight-speed automatic and front-drive are standard and all-wheel drive is optional. This popular midsize luxury crossover SUV is also a candidate that could hit the 250,000 mileage.

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